I'd go with Brady. Indy vs. NE will be a high scoring affair. Add to that San Diego is surprisingly good against the pass and will want to pound Denver with Tolbert to keep Orton on the sidelines and Brady is a great start this week.
I made the mistake of not going with Brady last week. I figured he wasn't going to do well against the Pittsburgh D. BOY was I wrong!!!! Pitts D is alot better than Indy's and Brady picked them apart. At home vs Indy?? No brainer for me.